| Sleep / Sleep Disorders / Insomnia News From Medical News Today |
Neurogen Announces Suspension Of Insomnia Study With Adipiplon
Neurogen Corporation (Nasdaq: NRGN) announced that, as planned, it commenced a Phase 2/3 clinical trial in chronic insomnia patients with the Company's insomnia agent, adipiplon and that, based upon reports from initial dosing of a higher than anticipated rate of unwanted next day effects, the Company has suspended dosing in the study. Neurogen believes that the bilayer tablet formulation of adipiplon being used in the study may not be performing as expected. |
Two New Studies Analyze Menopause-Related Sleep Problems
Two studies in the July 1 issue of the journal Sleep analyze menopausal sleep problems, finding that complaints may differ according to the stage of menopausal transition and the ethnicity of the woman, and identifying risk factors that may predict sleep problems at any stage of menopause. A multi-ethnic study of more than 3,000 women shows that the odds of having trouble falling asleep and staying asleep increase through the menopausal transition. |
Study Provides Evidence Of Brain Damage In Adults With Obstructive Sleep Apnea
A study in the July 1 issue of the journal Sleep provides visual evidence of the severe structural damage that occurs in numerous regions of the brain in people with obstructive sleep apnea (OSA). Results show that OSA patients have extensive alterations in "white matter," nerve tissue in the brain containing fibers that are insulated with myelin - a white, fatty sheath. |
Study Shows That Milder Forms Of Sleep-Disordered Breathing Are Associated With Hyperglycemia
A study in the July 1 issue of the journal Sleep shows that episodes of sleep-disordered breathing accompanied by mild oxygen desaturations of as little as two percent are associated with hyperglycemia. Adults with 11 or more apnea-hypopnea events per hour with an oxygen desaturation of 2.0 percent to 2.9 percent had an adjusted cumulative odds ratio of 1.41 for impaired fasting glucose or diabetes. |
Treating Pediatric Obstructive Sleep Apnea May Require A Combination Of Two Methods
Treating pediatric obstructive sleep apnea (OSA) with either orthodontic expansion or adenotonsillectomy improves symptoms, but most young children need both treatments to have complete resolution of OSA symptoms, according to a study in the July 1 issue of the journal Sleep. |
Difficulty Sleeping Increases As Women Progress Through Menopause According To Study By Rush University Medical Center
Difficulty falling asleep and staying asleep increase as women go through menopause according to research by Rush University Medical Center. Waking up earlier than planned also increases through late perimenopause but decreases when women become postmenopausal. The study is published in the July 1 issue of the journal SLEEP. |
Plants And Mammals Respond To Light In Similar Way
A new report published in the open-access journal PLoS Biology examines the effect that light has on humans and animals. Most of us are familiar with how light affects the growth and development of plants (phototropism, for example, describes how plants grow towards light), but researcher Nathalie Hoang and colleagues set out to explore light's impact on humans and mammals. |
Lack Of Fragile X And Related Gene Fractures Sleep
Lack of both the fragile X syndrome gene and one that is related could account for sleep problems associated with the disorder, which is the common cause of inherited mental impairment, said a consortium of researchers led by scientists at Baylor College of Medicine in Houston. Their findings appear in a report in the current issue of the American Journal of Human Genetics. |
Animal Study Suggests Inadequate Sleep May Exacerbate Cellular Aging In The Elderly
Researchers at the University of Pennsylvania School of Medicine have shown that the unfolded protein response, which is a reaction to stress induced by sleep deprivation, is impaired in the brains of old mice. The findings suggest that inadequate sleep in the elderly, who normally experience sleep disturbances, could exacerbate an already-impaired protective response to protein misfolding that happens in aging cells. |
Survey Shows Knee And Lower Back Pain Contribute To Insomnia, Weight Gain, Money Loss And More
What's the biggest pain in your life? Credit card debt? High gas prices? While these problems are extremely bothersome, a new survey from the makers of DR. SCHOLL'S® reveals that the physical pain suffered by people with knee and lower back pain is also at the top of the list. The survey shows that knee and lower back pain pervade many aspects of respondents' lives - and that's only the beginning of the story. |
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